Postdoctoral Fellow (Research Institute)

Do you want to work for a world-renowned research institute that pushes the boundaries of biomedical science and health research? Right here in Montreal! At the Research Institute of the McGill University Health Centre (RI-MUHC), you can be part of an organization focused on scientific discovery and innovation in patient-centered medicine. Join us today and make a difference!

Job Description

RESEARCH INSTITUTE OF THE MUHC

The Research Institute of the McGill University Health Centre (RI-MUHC) is a world-renowned biomedical and hospital research centre. Located in Montreal, Quebec, the Institute is the research arm of the McGill University Health Centre (MUHC) affiliated with the Faculty of Medicine at McGill University. The RI-MUHC is supported in part by the Fonds de recherche du Québec - Santé (FRQS).

Introduction

The Bateman Laboratory is seeking a postdoctoral fellow with an interest in developing biological therapies for the treatment of neurodegenerative diseases. The project is based on the neuroprotective activity of progranulin, particularly neurodegenerative disease associated with TDP-43 (Chitramuthu et al, Brain, 140, 2017, 3081–3104, Chitramuthu, PLoS ONE 12, 2017: e0174784, Doyle, PNAS, 118, 2021, e2022115118, Chitramuthu, Frontiers in Neuroscience, 15, 2022, 775391). The project will elucidate how the structure of progranulin relates to its activity both in neuroprotection and in neuromodulation, and how to leverage this information to develop novel therapeutic approaches to neurodegenerative diseases. It is a collaborative project with laboratories in University of Prince Edward Island and a Canadian company involved in drug development for neurodegenerative diseases. The studies will involve the genetic construction and production of modified forms of progranulin and their evaluation as leads towards new biological therapies. Knowledge of DNA manipulation and cell culture is essential.

Responsabilities And Objectives

• Actively designing and executing experiments,
• Creating DNA expression constructs, expression cell lines, RNA-seq,
• Developing and testing new research concepts,
• Applying for external fellowships,
• Writing manuscripts and grant applications,
• Ability to work independently or with teams with minimal supervision,
• Presenting and interpreting research data,
• Collaborating with team members.
  
  

Website of the organization

https://rimuhc.ca/en

Education / Experience

Education: Doctorate Degree

Field of Study: Molecular biosciences

• Experience constructing DNA vectors,
• Experience with molecular biology techniques
• Experience in cell culture techniques, microscopy.
  
  

Required Skills

• A PhD in molecular bioscience,
• RNA seq analysis
• Fluency in English (written and spoken)
• Excellent communication and interpersonal skills,
• Problem-solving, and trouble-shooting skills,
• Coordination with collaborators at other universities and commercial sites.
  
  

Additional information

Status: Temporary, full time

Site: GLEN Site, 1001 boul. Decarie

***If you wish to include a cover letter, please attach it with your resume in one document. ***

A Postdoctoral fellow is a full-time student currently enrolled in a Canadian University program. The individual must have recently been awarded (within 5 years) a PhD or equivalent. The Postdoctoral fellow will receive a stipend or a bursary from a professor’s grant for research activities that will be performed on a full-time basis. All benefits are administered by the University under which they are registered.

https://rimuhc.ca/careers

To learn more about our benefits, please visit http://rimuhc.ca/en/compensation-and-benefits

THIS IS NOT A HOSPITAL POSITION.

Equal Opportunity Employment Program

The Research Institute of the McGill University Health Centre hires on the basis of merit and is strongly committed to equity, diversity and inclusion within its community. We welcome applications from all qualified candidates who self-identify as members of racialized groups/visible minorities, women, Indigenous persons, persons with disabilities, ethnic minorities, and 2SLGBTQIA+ persons. We also welcome candidates with the skills and knowledge to productively engage with diverse communities. Persons with disabilities who anticipate needing accommodations for any part of the application process may confidentially contact, [email protected]